Characteristics of Increased Serum Amyloid A (SAA) and a1•Acid Glycoprotein (AAG) Concentrations in Cats Subjected to Experimental Surgical Treatments or Inoculated with Bordetella bronchiseptica
نویسندگان
چکیده
The concentrations of serum amyloid A (SAA) and a1•acid glycoprotein (AAG) in the serum of 11 healthy cats subjected to oophorohysterectomy (5 females) and gastrotomy (3 males, 3 females) were measured by turbidimetric immunoassay (TIA) for human SAA (human SAA-TIA) and single radial immunodiffusion (SRID) kits for feline AAG, respectively. Six healthy cats (3 males, 3 females) were inoculated intrabronchially with 2 × 109 live, avirulent cells of Bordetella bronchiseptica as a model of transient bronchopneumonia in order to investigate serum concentrations of SAA and AAG, as well as white blood cell (WBC) counts and antibody responses to B. bronchiseptica in sera by indirect fluorescence antibody technique (IFA). Peak concentrations of SAA after oophorohysterectomy and gastrotomy were 4.8 to 26.8 times and 11.5 to 23.4 times higher than preCharacteristics of Increased Serum Amyloid A (SAA) and a1•Acid Glycoprotein (AAG) Concentrations in Cats Subjected to Experimental Surgical Treatments or Inoculated with Bordetella bronchiseptica Takuo Shida1, DVM, Ms, PhD Takashi Kuribayashi2, DVM, Ms, PhD
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